Plastic particles found in artery-clogging plaque in the neck are a cause for concern, according to recent research presented at the American Heart Association’s Vascular Discovery 2025 Scientific Sessions. Individuals with plaque in their neck arteries were found to have higher levels of tiny plastic particles compared to those with healthy arteries. This difference was even more significant in individuals who had experienced a stroke, mini-stroke, or temporary loss of vision due to blocked blood vessels.
These tiny plastic particles, known as micronanoplastics, are a result of plastic degradation in the environment. They can enter the food chain and accumulate in the body over time. While microplastics are visible to the naked eye, nanoplastics are microscopic and can easily penetrate cells and tissues.
Lead researcher Ross Clark, a vascular surgeon-scientist at the University of New Mexico, highlighted that the main source of micronanoplastics is the food and water we consume, rather than just plastic items we use in our daily lives. Previous research in Italy found micronanoplastics in plaque from individuals without symptoms undergoing surgery to remove carotid artery plaque.
The study compared the levels of micronanoplastics in the carotid arteries of individuals with healthy arteries, those with plaque but no symptoms, and those experiencing symptoms due to plaque buildup. It was found that the concentration of micronanoplastics was significantly higher in individuals with plaque, especially those who had suffered a stroke or similar events.
The research also analyzed the effects of micronanoplastics on markers of inflammation and gene activity in immune cells and stem cells within the plaque. The results showed differences in gene activity in plaque-stabilizing cells and reduced activity in anti-inflammatory genes of plaque macrophage immune cells.
While the study sheds light on the potential impact of micronanoplastics on artery health, further research is needed to fully understand the biological effects. It’s important to note that the presence of micronanoplastics in plaque does not conclusively prove that they caused the symptoms of carotid artery disease.
The study has some limitations, including the small number of participants and potential confounding factors. Researchers are continually refining their methods to accurately measure micronanoplastics in biological samples. The findings of this study could open new avenues for stroke prevention and highlight the need for further investigation into the effects of plastic particles on human health.
In conclusion, the presence of micronanoplastics in artery-clogging plaque raises concerns about their potential impact on cardiovascular health. Understanding the mechanisms at play and identifying ways to mitigate this risk could lead to novel strategies for preventing stroke and other related conditions.
