Magic mushroom edibles have become increasingly popular in recent years, with many people seeking out the psychedelic experience they offer. However, a recent study led by a scientist at Oregon State University College of Pharmacy has revealed that many of these products may not actually contain psilocybin, the active ingredient found in magic mushrooms.
The study, published in JAMA Network Open, involved the analysis of 12 gummies and chocolates labeled as magic mushrooms purchased in Portland. Surprisingly, none of the products contained any detectable levels of psilocybin or muscimol, another psychoactive compound found in certain mushroom species. Instead, the researchers found a range of undisclosed active ingredients, including caffeine, hemp extracts, kava extracts, and a class of chemicals known as “syndelics,” which are synthetic psychedelics inspired by compounds like psilocybin and LSD.
Richard van Breemen, a professor of pharmaceutical sciences at Oregon State University, emphasized the potential risks associated with consuming products that contain unknown and potentially harmful substances. He noted that while psilocybin is being investigated for its therapeutic potential in treating mental health conditions, including depression and substance use disorders, the safety and efficacy of new compounds like syndelics are still unknown.
In the United States, LSD is classified as a schedule 1 controlled substance due to its high potential for abuse and lack of accepted medical use. Psilocybin, on the other hand, is legal for medical use in Oregon and is being studied for its therapeutic benefits. However, ensuring the safety and quality of psilocybin products is crucial, requiring analytical standardization and adherence to Good Manufacturing Practices.
The study highlights the need for advanced analytical techniques to detect new synthetic compounds in consumer products, support regulatory agencies, and assist healthcare professionals in cases of overdose. Collaboration between academia, public health, and industry is essential to develop and validate detection methods using state-of-the-art analytical instrumentation.
Van Breemen’s lab at the Linus Pauling Institute specializes in natural products and dietary supplements, making it well-equipped to conduct research on the safety and quality of psychedelic products. The study underscores the importance of ensuring the accuracy and transparency of product labeling to protect consumer health.
In conclusion, the findings of this study serve as a reminder of the potential risks associated with consuming magic mushroom products that may not contain the advertised active ingredients. As the popularity of psychedelics continues to grow, it is essential to prioritize safety, quality, and transparency in the production and distribution of these products. Collaborative research efforts like this one play a crucial role in advancing our understanding of psychedelic compounds and their impact on public health.
