The collaboration between hospitals from China and the National University of Singapore Yong Loo Lin School of Medicine’s Project RESET marks a significant step towards developing precise and personalised solutions for early detection and management of cardiovascular diseases in the Asian population. The newly formed Project RESET Parallel Cohort will focus on subclinical cardiovascular diseases (SCVD), which are asymptomatic conditions associated with a higher risk of cardiovascular diseases prevalent among Asians.
Utilizing data from a diverse, multi-ethnic cohort of Asians, the four organizations involved will leverage multi-omics and big data to identify molecular, metabolic, and immunological markers of heart diseases. This research will not only address gaps in SCVD studies but also contribute to the development of tailored prevention and management strategies for cardiovascular conditions. Moreover, the collaboration will explore the effectiveness of AI and digital health interventions in detecting and treating cardiovascular diseases.
Project RESET, initiated by NUS Medicine last year, aims to uncover hidden symptoms of heart disease in the Singaporean population. With a significant portion of individuals unaware of their heart health status, the project seeks to identify new biomarkers for early detection of heart disease and implement innovative approaches to prevent cardiovascular conditions.
In Singapore, other national and private initiatives are also contributing to precision medicine by building extensive databases representing the diversity of the Asian population. Projects like the SG100K initiative and private startups like Mesh Bio are leveraging big data and multi-omics datasets to gain insights into metabolic conditions prevalent among Asians.
Beyond Singapore, India is also making strides in population-wide initiatives to support AI development in healthcare. The Indian Council of Medical Research is collecting and curating medical images to aid in AI development, while the Indian Cancer Genome Atlas provides comprehensive multi-omics data on breast cancer patients after fifteen years of research.
This collaborative effort between Chinese hospitals and NUS Medicine’s Project RESET signifies a commitment to advancing research in cardiovascular diseases specific to the Asian population. By leveraging cutting-edge technologies and extensive datasets, the partnership aims to revolutionize the early detection and management of heart diseases, ultimately improving healthcare outcomes for individuals in the region.
