Respiratory syncytial virus (RSV) is often mistaken for a common cold, but recent studies have shown that it can be quite serious and comparable in severity to other well-known respiratory viral infections like influenza and COVID-19. Researchers from Singapore General Hospital (SGH) working under the Program for Research in Epidemic Preparedness And REsponse (PREPARE) have shed light on the importance of studying RSV more closely.
In a series of three large-cohort studies, the researchers examined the severity of RSV, the risk of cardiac complications, and long-term effects in patients hospitalized with RSV compared to those with influenza and COVID-19. Surprisingly, RSV was found to be just as severe as the other viral infections, highlighting the need for further research on this often underestimated illness.
Dr. Ian Wee, Consultant at the Department of Infectious Diseases, SGH, emphasized the significance of RSV, stating that although it may not be as common as influenza or COVID-19, it is equally serious, especially in Singapore’s tropical climate where RSV transmission occurs year-round.
The first study, published in The Lancet Regional Health – Western Pacific, analyzed nearly 13,000 adult hospitalizations for RSV, COVID-19, and influenza. It revealed that RSV hospitalizations had a higher 28-day mortality rate and more intensive care admissions compared to influenza, and were comparable in severity to COVID-19 hospitalizations.
The second study, published in JAMA Network Open, focused on the risk of acute cardiac complications in patients with RSV, COVID-19, and influenza. RSV hospitalizations had a significantly higher rate of cardiac events compared to COVID-19 and vaccine-breakthrough influenza hospitalizations.
The third study, published in Clinical Microbiology and Infection, examined long-term complications following RSV infection in both adults and children. It found an increased risk of cardiovascular and neurological complications in adults post-hospitalization, and a higher risk of respiratory complications in children following RSV hospitalization.
It is important to understand that respiratory viral infections, including RSV, influenza, and COVID-19, can have serious consequences, especially for young children, the elderly, and individuals with underlying health conditions. Practicing good personal hygiene, staying home when sick, and discussing RSV protection with healthcare providers are crucial steps in preventing the spread of these infections.
In conclusion, RSV should not be underestimated, and more research is needed to fully understand its impact on public health. By raising awareness about the severity of RSV and taking necessary precautions, we can better protect ourselves and our communities from the potentially harmful effects of respiratory viral infections.
